Rebecca J Willcocks,
Research Assistant Professor
Teaching Profile
Courses Taught
2020-2021,2024-2025
HSC4913 Supervised Research Experience
2019-2021,2023-2024
HSC4970 Public Health and Health Professions Senior Honors Thesis
2019-2025
OTH3413C Applied Kinesiology
2018
PHT6152C Exercise Physiology
2021,2024
HSC4905 Individual Study
2021-2025
PHT6153 Physiology for Pt
2022-2024
RSD6910 Supervised Research
2023-2025
RSD7979 Advanced Research
2024-2025
RSD6940 Supervised Teaching
2024
RSD6905 Individual Work
Publications
Academic Articles
2024
A model-informed clinical trial simulation tool with a graphical user interface for Duchenne muscular dystrophy.
CPT: pharmacometrics & systems pharmacology.
[DOI] 10.1002/psp4.13246.
[PMID] 39360574.
2024
Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy.
Annals of clinical and translational neurology.
11(1):67-78
[DOI] 10.1002/acn3.51933.
[PMID] 37932907.
2024
Five multivariate Duchenne muscular dystrophy progression models bridging six-minute walk distance and MRI relaxometry of leg muscles.
Journal of pharmacokinetics and pharmacodynamics.
51(6):671-683
[DOI] 10.1007/s10928-024-09910-1.
[PMID] 38609673.
2023
Givinostat for Becker muscular dystrophy: A randomized, placebo-controlled, double-blind study.
Frontiers in neurology.
14
[DOI] 10.3389/fneur.2023.1095121.
[PMID] 36793492.
2023
Multivariate modeling of magnetic resonance biomarkers and clinical outcome measures for Duchenne muscular dystrophy clinical trials.
CPT: pharmacometrics & systems pharmacology.
12(10):1437-1449
[DOI] 10.1002/psp4.13021.
[PMID] 37534782.
2022
Characterization of patients with Becker muscular dystrophy by histology, magnetic resonance imaging, function, and strength assessments.
Muscle & nerve.
65(3):326-333
[DOI] 10.1002/mus.27475.
[PMID] 34918368.
2022
Characterizing Expiratory Respiratory Muscle Degeneration in Duchenne Muscular Dystrophy Using MRI.
Chest.
161(3):753-763
[DOI] 10.1016/j.chest.2021.08.078.
[PMID] 34536384.
2022
Development of Contractures in DMD in Relation to MRI-Determined Muscle Quality and Ambulatory Function.
Journal of neuromuscular diseases.
9(2):289-302
[DOI] 10.3233/JND-210731.
[PMID] 35124659.
2022
Evaluating Genetic Modifiers of Duchenne Muscular Dystrophy Disease Progression Using Modeling and MRI.
Neurology.
99(21):e2406-e2416
[DOI] 10.1212/WNL.0000000000201163.
[PMID] 36240102.
2022
Longitudinal changes in cardiac function in Duchenne muscular dystrophy population as measured by magnetic resonance imaging.
BMC cardiovascular disorders.
22(1)
[DOI] 10.1186/s12872-022-02688-5.
[PMID] 35681116.
2022
Step Activity Monitoring in Boys with Duchenne Muscular Dystrophy and its Correlation with Magnetic Resonance Measures and Functional Performance.
Journal of neuromuscular diseases.
9(3):423-436
[DOI] 10.3233/JND-210746.
[PMID] 35466946.
2021
Assessment of rAAVrh.74.MHCK7.micro-dystrophin Gene Therapy Using Magnetic Resonance Imaging in Children With Duchenne Muscular Dystrophy.
JAMA network open.
4(1)
[DOI] 10.1001/jamanetworkopen.2020.31851.
[PMID] 33394000.
2021
Disease-modifying effects of edasalonexent, an NF-κB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial.
Neuromuscular disorders : NMD.
31(5):385-396
[DOI] 10.1016/j.nmd.2021.02.001.
[PMID] 33678513.
2021
Walking activity in a large cohort of boys with Duchenne muscular dystrophy.
Muscle & nerve.
63(2):192-198
[DOI] 10.1002/mus.27119.
[PMID] 33188573.
2020
Characterizing Enrollment in Observational Studies of Duchenne Muscular Dystrophy by Race and Ethnicity.
Journal of neuromuscular diseases.
7(2):167-173
[DOI] 10.3233/JND-190447.
[PMID] 31929119.
2020
Conference report on contractures in musculoskeletal and neurological conditions.
Muscle & nerve.
61(6):740-744
[DOI] 10.1002/mus.26845.
[PMID] 32108365.
2020
Lower Extremity Muscle Involvement in the Intermediate and Bethlem Myopathy Forms of COL6-Related Dystrophy and Duchenne Muscular Dystrophy: A Cross-Sectional Study.
Journal of neuromuscular diseases.
7(4):407-417
[DOI] 10.3233/JND-190457.
[PMID] 32538860.
2020
Magnetic Resonance Imaging Studies in Duchenne Muscular Dystrophy: Linking Findings to the Physical Therapy Clinic.
Physical therapy.
100(11):2035-2048
[DOI] 10.1093/ptj/pzaa140.
[PMID] 32737968.
2020
Modeling disease trajectory in Duchenne muscular dystrophy.
Neurology.
94(15):e1622-e1633
[DOI] 10.1212/WNL.0000000000009244.
[PMID] 32184340.
2020
MR biomarkers predict clinical function in Duchenne muscular dystrophy.
Neurology.
94(9):e897-e909
[DOI] 10.1212/WNL.0000000000009012.
[PMID] 32024675.
2020
Upper and Lower Extremities in Duchenne Muscular Dystrophy Evaluated with Quantitative MRI and Proton MR Spectroscopy in a Multicenter Cohort.
Radiology.
295(3):616-625
[DOI] 10.1148/radiol.2020192210.
[PMID] 32286193.
2019
Imaging respiratory muscle quality and function in Duchenne muscular dystrophy.
Journal of neurology.
266(11):2752-2763
[DOI] 10.1007/s00415-019-09481-z.
[PMID] 31350642.
2019
Lower Extremity Functional Outcome Measures in Duchenne Muscular Dystrophy-A Delphi Survey.
Journal of neuromuscular diseases.
6(1):75-83
[DOI] 10.3233/JND-180337.
[PMID] 30562905.
2019
Magnetic resonance imaging characteristics of injection site reactions after long-term subcutaneous delivery of drisapersen.
European journal of pediatrics.
178(5):777-778
[DOI] 10.1007/s00431-019-03349-0.
[PMID] 30790036.
2018
Leg muscle MRI in identical twin boys with duchenne muscular dystrophy.
Muscle & nerve.
[DOI] 10.1002/mus.26081.
[PMID] 29365354.
2018
Longitudinal timed function tests in Duchenne muscular dystrophy: ImagingDMD cohort natural history.
Muscle & nerve.
58(5):631-638
[DOI] 10.1002/mus.26161.
[PMID] 29742798.
2018
Skeletal muscle magnetic resonance biomarkers correlate with function and sentinel events in Duchenne muscular dystrophy.
PloS one.
13(3)
[DOI] 10.1371/journal.pone.0194283.
[PMID] 29554116.
2018
Two-Year Longitudinal Changes in Lower Limb Strength and Its Relation to Loss in Function in a Large Cohort of Patients With Duchenne Muscular Dystrophy.
American journal of physical medicine & rehabilitation.
97(10):734-740
[DOI] 10.1097/PHM.0000000000000957.
[PMID] 29734234.
2017
Magnetic resonance imaging of the proximal upper extremity musculature in boys with Duchenne muscular dystrophy.
Journal of neurology.
264(1):64-71
[DOI] 10.1007/s00415-016-8311-0.
[PMID] 27778157.
2017
Multi-slice MRI reveals heterogeneity in disease distribution along the length of muscle in Duchenne muscular dystrophy.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology.
36(3):151-162
[PMID] 29774305.
2016
MRI quantifies neuromuscular disease progression.
The Lancet. Neurology.
15(1):26-8
[DOI] 10.1016/S1474-4422(15)00320-8.
[PMID] 26549781.
2016
Multicenter prospective longitudinal study of magnetic resonance biomarkers in a large duchenne muscular dystrophy cohort.
Annals of neurology.
79(4):535-47
[DOI] 10.1002/ana.24599.
[PMID] 26891991.
2014
Chemical shift-based MRI to measure fat fractions in dystrophic skeletal muscle.
Magnetic resonance in medicine.
72(1):8-19
[DOI] 10.1002/mrm.24917.
[PMID] 24006208.
2014
Examination of effects of corticosteroids on skeletal muscles of boys with DMD using MRI and MRS.
Neurology.
83(11):974-80
[DOI] 10.1212/WNL.0000000000000775.
[PMID] 25098537.
2014
Global T2 versus water T2 in NMR imaging of fatty infiltrated muscles: different methodology, different information, and different implications.
Neuromuscular disorders : NMD.
24(12):1120-1
[DOI] 10.1016/j.nmd.2014.07.002.
[PMID] 25153266.
2014
Longitudinal measurements of MRI-T2 in boys with Duchenne muscular dystrophy: effects of age and disease progression.
Neuromuscular disorders : NMD.
24(5):393-401
[DOI] 10.1016/j.nmd.2013.12.012.
[PMID] 24491484.
2014
Magnetic resonance imaging and spectroscopy assessment of lower extremity skeletal muscles in boys with Duchenne muscular dystrophy: a multicenter cross sectional study.
PloS one.
9(9)
[DOI] 10.1371/journal.pone.0106435.
[PMID] 25203313.
2013
Magnetic Resonance Imaging and Spectroscopy Detect Changes With Age, Corticosteroid Treatment, and Functional Progression in Dmd
Neuromuscular Disorders.
23(9-10)
[DOI] 10.1016/j.nmd.2013.06.599.
2013
Skeletal muscles of ambulant children with Duchenne muscular dystrophy: validation of multicenter study of evaluation with MR imaging and MR spectroscopy.
Radiology.
269(1):198-207
[DOI] 10.1148/radiol.13121948.
[PMID] 23696684.
2011
Design of a Multi-Center Study To Examine Skeletal Muscles of Children With Duchenne Muscular Dystrophy Using Mri/Mrs
Neuromuscular Disorders.
21(9-10):653-654
[DOI] 10.1016/j.nmd.2011.06.801.
2010
Age- and sex-related differences in muscle phosphocreatine and oxygenation kinetics during high-intensity exercise in adolescents and adults.
NMR in biomedicine.
23(6):569-77
[DOI] 10.1002/nbm.1495.
[PMID] 20661873.
2010
Commentaries on Viewpoint: Do oxidative and anaerobic energy production in exercising muscle change throughout growth and maturation? The importance of exercise intensity when studying developmental energy metabolism.
Journal of applied physiology (Bethesda, Md. : 1985).
109(5):1565-6
[DOI] 10.1152/japplphysiol.00986.2010.
[PMID] 21171239.
Presentations
2022-10-11
Minimum clinically important difference in magnetic resonance biomarkers in DMD
International
/
Refereed.
Poster.
Halifax, Canada
2022-12-01
Correlation of Imaging and Function.
International
/
Invited.
Lecture.
Washington, DC
2023-03-19
Leg muscle MR biomarkers are responsive to disease progression after loss of ambulation and strongly correlate with upper extremity function. Muscular Dystrophy Association.
National
/
Refereed.
Poster.
Dallas, Texas
2023-03-19
MRI fat fraction of arm and leg muscles is correlated with function in Becker muscular dystrophy
National
/
Refereed.
Poster.
Dallas, Texas
2023-10-03
Bone marrow fat fraction is elevated in corticosteroid-treated boys with Duchenne muscular dystrophy
International
/
Refereed.
Poster.
Charleston, USA
Grants
Sep 2021
ACTIVE
MR Biomarkers of Bone Quality in DMD
Role: Principal Investigator
Funding: US ARMY MED RES ACQUISITION
Sep 2021
– Jul 2024
Optimizing Muscular Dystrophy Clinical Trial Designs using Modeling and Simulation
Role: Co-Investigator
Funding: NATL INST OF HLTH NCATS
Sep 2020
ACTIVE
Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Jul 2019
– Jun 2024
OoR Matching Support for CTSI
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Education
PhD
2007-2011
·
University of Exeter
MSc
2006-2007
·
University of Exeter
BSc
2000-2006
·
University of Victoria
Contact Details
Phones:
- Business:
- (352) 294-5997
Emails:
- Business:
- rw254@phhp.ufl.edu
Addresses:
- Business Mailing:
-
PO BOX 100154
DEPARTMENT OF PHYSICAL THERAPY
GAINESVILLE FL 326100154